What are Triple-immunodeficient mice? 

The triple-immunodeficient mice can host xenograft cells, tissues, and components of the human immune system, allowing studies of tumor biology and immuno-oncology, infectious diseases, graft-versus-host disease (GvHD), hematopoiesis, and tissue transplantation. Infectious diseases, oncology, immunology, and regenerative medicine labs use triple-immunodeficient mice. Immuno-compromised animals are used in cancer, immunology, stem cell, and infectious disease research. 

How do SCID mouse models work? How can SCID mice be used in research? 

SCID mice have B and T lymphocyte deficiencies caused by a genetic autosomal recessive mutation. Models based on SCID are ideal for immune system studies but can also be applied to tumor growth studies and lymphocyte development and function. 

What are Nude Mice? 

Nude mice have a genetic mutation that prevents them from having a normal immune system and thymus gland. These mice have a repressed immune system due to the reduction of T cells. Due to their lack of rejection response, naked mice are often used for tissue and tumor grafts in cancer research.